It is essential to avoid introducing presuppositions in understanding and interpreting the Quran, but this does not mean that various scientific and intellectual knowledge and findings cannot and should not play a role in understanding and interpreting the Quran. Allama Tabataba'i's intellectual and philosophical insight has given Tafsir al-Mizan a special place among commentators; for example, he has been able to interpret the issue of Asm'a and Elm al-asm'a in verses 30 to 33 of Surah Al-Baqarah in a much more profound way by utilizing his intellectual and philosophical knowledge, without going beyond the framework of the correct method of interpretation and imposing a presupposition on the verses of the Quran. Allama's answer to the question of what is meant by names and the science of names and what is the connection between the science of names and the qualification for the divine caliphate is that these names or their attributes are supreme beings in the presence of Allah; They are actually superior beings to earthly beings, including Adam himself, and they are the mediators of divine grace to inferior beings, and the relationship between them and earthly beings is a cause-and-effect relationship. Adam’s knowledge of the names or the names of the names is a present knowledge, unlike the knowledge of the angels, which is an acquired knowledge and was obtained by teaching Adam. His present knowledge of the names and means of divine grace, which is a sign of his existential connection with them, is the criterion for his caliphate and his suitability to succeed God on earth. The present article has been conducted using an analytical-descriptive method and a comparison between philosophy and the Quran.